Vyvanse and grapefruit

Vyvanse and grapefruit DEFAULT

Can you make Vyvanse last longer?

If you take a regular dose of Vyvanse, one of the prescription drugs used to treat attention deficit hyperactivity disorder (ADHD), you might worry that the intended effect will dwindle before you’ve crossed everything off your to-do list.

How long does Vyvanse last?

Vyvanse improves focus for up to 14 hours. Yet, many have asked how to make it last even longer, or intensify its effects.  

“No ADHD medication lasts as long as we would like,” said Dr. Daniel Lieberman, professor of psychiatry and behavioral sciences at the George Washington University School of Medicine and Health Sciences. “It typically lasts eight to 10 hours, but we don’t live in a 9-to-5 world. Patients may need to get 12 or more hours out of a stimulant.”

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How to make Vyvanse last longer

An online search for “how to make Vyvanse last longer” will bring up countless ways to potentially increase the duration of the drug’s effects. Is there any truth behind these claims? Not really.

While some people say that combining magnesium and Vyvanse, avoiding dairy and coffee, taking gingko pills and eating large meals make Vyvanse last longer, there’s no proof that these strategies actually work, said Lieberman.

However, there are a few things that might influence the drug performance or how you perceive its effects:

  • Protein: “It has the potential to boost the same brain chemicals that Vyvanse is boosting. The protein won’t have an effect on the drug, but it augments the effects of the medication,” said Lieberman.
  • Exercise: “A lot of people with ADHD also have depression at the same time, and both conditions may make it difficult to focus and concentrate. Exercise may help with those symptoms,” said Lieberman.
  • Vitamin C: “Orange juice and other things with vitamin C might have the potential to slow down the body’s ability to convert Vyvanse into active amphetamine. It may make it last longer, but the overall effect will be less—it’s like eating a bag of popcorn more slowly,” said Lieberman.

He added that drinking a lot of grapefruit juice is a very bad idea. “Grapefruit juice can slow down the rate at which the body gets rid of drugs, which can be dangerous,” he explained. It’s important to note, a lot of patients taking ADHD medication are also taking other psychiatric medications to treat related conditions like depression and anxiety. Many of these prescriptions, such as SSRIs and tricyclic antidepressants, can have a dangerous drug-drug interaction with Vyvanse that’s similar to the interaction with grapefruit juice.

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Understanding Vyvanse

When you first start taking Vyvanse (What is Vyvanse?), you might experience a boost in energy, motivation and positivity. However, these effects don’t typically last, said Dr. Lieberman.

“If you’re finding the increased energy is wearing off, tough luck—that’s not what the drug’s supposed to do,” he said. “Vyvanse is supposed to improve focus, concentration and impulse control. When you focus on those three things, people find it lasts longer than they thought.”

Rather than looking for ways to make Vyvanse last longer, here are some tips on having the best experience on the medication, to make Vyvanse work better for you:

  • Find the right dose: Vyvanse offers seven different capsule strengths, ranging from 10-70 mg. The typical starting dose is 30mg, and dosages are increased in 10mg to 20mg increments after monitoring response. Work with your doctor to measure the drug’s effect on your focus, concentration and impulse control to find the right dose, said Lieberman.
  • Ask for feedback: Not sure if your Vyvanse is working? Ask your significant other or coworkers if they see improvements in your focus as you try different strengths. “Third-party feedback will help us decide if a higher dose is doing something,” said Lieberman.
  • Break bad habits: “People with ADHD often develop some bad habits, like running late or losing things. Psychiatric drugs make it easier to break those habits, but it will still take work,” he said. Lieberman suggests working with a mental health professional to make behavioral changes (like using calendars and removing distractions from your workspace) to complement the effects of the drug.

RELATED: ADHD treatment and medications

If you’re finding that Vyvanse isn’t working well, or lasting as long as you’d like, talk to your doctor. There are many different ADHD medications that are very effective when you find the right dosage.

Sours: https://www.singlecare.com/blog/can-you-make-vyvanse-last-longer/

How To Intensify Vyvanse – What To Take, What To Do, A Guide

Posted February 26, 2020 by Michael Chamberlain - See Editorial Guidelines
how to intensify Vyvanse

Vyvanse is a medication prescribed for ADHD (attention deficit hyperactivity disorder). This is a controlled substance, so doctors usually prescribe small doses. The strength of Vyvanse wears off over time. So, many patients search for ways to intensify Vyvanse throughout the day.

However, increasing the dosage more than the prescribed amount may be considered drug abuse and can result in several side effects and life-threatening risks.

So, this article will give a clear overview of how to intensify Vyvanse and things to avoid in order to make it last longer, as well as other alternative methods that can be used.

But first, here’s the quick list for you, then we’ll take some time to go into greater depth.

How To Intensify Vyvanse? The following are some common methods to intensify Vyvanse, 

  • Magnesium or Gingko pills may intensify Vyvanse
  • Include enough protein in your diet
  • Maintain a steady exercise schedule 
  • Avoid vitamin C products, acidic juices, and caffeine 
  • Learn about drug interactions that makes Vyvanse less effective

However, these small doses may not be enough for one to carry out the daily list of chores, needs, and wants. In today’s culture, more and more people are working for more than 8-9 hours, and you need to keep the busy days running along.

First, let’s take a look at how long Vyvanse gives you in a standard dose.

How Long Does Vyvanse Last?

How To Intensify Vyvanse

On average, Vyvanse lasts for about 10-14 hours. However, most patients report they experience the effects of this medication for only around 8 hours. So, this means the symptoms of ADHD are only under control within these hours, and it will eventually wear off. This makes it difficult to focus or concentrate for the rest of the day.

Experts and medical professionals say Vyvanse could last up to 8-10 hours and will typically wear off by evening, provided that Vyvanse is often prescribed to be taken in the morning.

It’s also said that several factors interfere and disturb the functioning of this medication – and its overall strength.

How To Intensify Vyvanse

So, how do we increase the effectiveness of Vyvanse? Well, there are several methods recommended to intensify Vyvanse. Even many online searches bring countless ways to increase the duration and strength of how Vyvanse works.

Not all these methods may be useful or provide improvements, so it’s always better to check these measures yourself, and then choose what’s useful for you as an individual.

From us, the following methods and measures are found to be effective and work well among patients to intensify Vyvanse.

Magnesium Or Ginkgo Pills May Intensify Vyvanse

Combining magnesium and ginkgo may help in intensifying Vyvanse. This method will also help Vyvanse last longer than the average duration (but this should be done only after appropriate consultation with the doctor).

Some recommend that taking Ginkgo pills intensify Vyvanse while making it last longer (This again should be done after appropriate consultations with your doctor).

Intensify Vyvanse

Include Enough Protein In Your Diet

Consuming enough protein in your diet may help in intensifying Vyvanse. This is because proteins can boost the brain chemicals, which Vyvanse is already increasing.

This will thereby improve the focus and concentration of patients. The protein doesn’t have a direct effect on the medication, but it improves the controlling ability of the medication, intensifying the effects of the meds overall.

Maintain An Exercise Schedule

Exercising has been known to improve the intensifying and long-lasting effects of Vyvanse.

This is because many patients taking ADHD medication like Vyvanse experience depression, which can make the medication less effective, and even the effects of these medications are experienced only for a short period.

It’s this depression that makes patients feel unfocused. Patients may find it challenging to concentrate within a few hours of taking Vyvanse. So, to eliminate symptoms of depression and to make the effects of the medication last longer, exercise and fitness most certainly help.

Avoid Vitamin C Products, Acidic Juices, And Caffeine

How To Intensify Vyvanse

Vitamin C products, especially grapefruit juice, oranges, and orange juice, should be avoided.

Vitamin C slows down the body’s natural ability to absorb and convert Vyvanse into active amphetamine. This results in a reduction not only in the duration of which Vyvanse can last but also reduces its overall effects in controlling ADHD symptoms.

Avoiding grapefruit juices and any other acidic juices are encouraged to intensify Vyvanse. Acidic drinks interfere and interact with Vyvanse reducing its long-lasting features and strength, but they also reduce the rate at which a body can get rid of the medication. This can be dangerous, especially for a controlled substance like Vyvanse.

Avoid consuming any dairy or coffee related food or liquid. Caffeine is believed to interfere with the proper functioning of the medication within the system, making Vyvanse less intense.

Drug Interactions That Make Vyvanse Less Effective

Certain patients also consume several psychiatric medications in parallel to Vyvanse. These medications are mostly taken to control symptoms like depression and anxiety that come with taking ADHD medications.

These medications may interfere and even interact with Vyvanse, reducing the long-lasting effect and overall strength of Vyvanse.

It’s important to note here that the interaction of Vyvanse and any other psychiatric medication is generally considered dangerous, so consult your doctor and adhere to medical advice.

Similar to many drug interactions, any other medications that increase the acidity of one’s blood will make Vyvanse less strong and less intense. Some examples of such medicines include aspirin, penicillin, and furosemide. It’s recommended to ask your doctor or pharmacist about specific interactions with Vyvanse.

Certain other medications reduce the acidity of the blood. Such medications include sodium bicarbonate (found in Zegerid), Benadryl, and Metoprolol. Reducing the acidity in the blood will help in intensifying Vyvanse more than the expected results.

Note – When taking any medications along with Vyvanse, it’s recommended
that you get them approved by your doctor or pharmacist.

Discuss Dosage Options with Your Doctor

Some patients may think that either increasing the dose or taking a second dose will give them the effect they are looking for. We DO NOT recommend this.

Taking a full second dose will be stronger and more intense than necessary and may affect the system and even potentially cause severe addiction over time. Both of these options will result in adverse side effects that can be deadly in some cases.

If you believe that you need a stronger dose, then consult your doctor. Discuss your symptoms with your physician to determine if this is the right course of action.

To Finish

We hope this has given you some practical guidelines to follow to get the most out of your Vyvanse medication. It’s crucial that you adhere to your doctor’s advice when it comes to taking your medication.

If you have any questions about how Prescription Hope can help you save money for any other drugs that we offer, or if you’re having trouble affording any of the medications you’ve been prescribed, then contact us. Visit the enrollment page to create an account and fill out a simple application and let us save you money!


Sours: https://prescriptionhope.com/blog-how-to-intensify-vyvanse-what-to-take-what-to-do-a-guide/
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Four Common ADHD Medication Mistakes and How To Avoid Them

As an adult ADHD coach, my clients and I talk about many ways to make life with ADHD easier.

When we focus on the details of their ADHD treatment, finding they are making common ADHD medication mistakes isn’t unusual.

Adults with ADHD don’t do this intentionally. Most people just don’t know what prevents ADHD meds from working correctly.

We traditionally think that you get up, take your medication and go about your day.

BUT there truly are simple day-to-day activities that can hinder the effectiveness of your medication. 

Four ADHD Medication Mistakes and How to Avoid Them

ADHD Medication Mistake #1: Drinking citrus juice. 

The acid in oranges, grapefruits, and vitamin C interrupts the absorption of ADHD medications. The short acting Adderall and Ritalin. And, the long acting medications such as Vyvance and Concerta, too. That’s because they start with a short acting boost to quickly kick your brain into gear. 

According to Dr William Dobson, high doses of vitamin C (1000 mg.), in pill or juice form, can also speed up the excretion of the medication in the urine so it moves out of your system too quickly.

So drinking that glass of orange juice or grapefruit juice when you take your Adderall or Ritalin is a no-no. 

You don’t have to give up your daily glass of juice or Vitamin C pill. Wait about an hour before and after you take medication. By then the drug has moved through your system where the acid in the citrus won’t interfere.

People have different experiences with this. It’s easy to test it out on yourself. 

ADHD Medication Mistake #2: Not eating breakfast. 

It doesn’t matter if you’re late or you don’t like to eat in the morning. It’s important to eat something before you take your ADHD medication. Your meds will work better and you’ll have fewer side effects. And you’ll get a meal in before the medication suppresses your appetite.

You don’t have to eat a big meal. Some people aren’t breakfast eaters and many people with ADHD run late in the morning. 

Even a small, healthy, protein-based snack will help. A healthy protein bar or drink (read the labels and watch for extra sugar). A banana and a handful of almonds. Peanut butter toast. Microwave an egg with some salsa added (coconut oil will make the bowl easier to wash!).

ADHD Medication Mistake #3: Not drinking enough water. 

Stimulant ADHD medications are dehydrating. Dehydration causes brain fog. 99% of my new coaching clients don’t drink enough water whether or not they treat their ADHD with medication. Hydrate up. If you want your brain to work it’s important. 

My first sign that I’m dehydrated is brain fog. The stronger sign is a headache. When dehydration goes to headache stage it can take a couple of days of focused water drinking to recover.

Drinking enough water is an easy way to help your ADHD medication work for you! 

ADHD Medication Mistake #4: Forgetting to refill your prescription. 

Ever experience the panic of taking your last Adderall on a Sunday morning? You need your ADHD medication to focus at work on Monday and there’s no way to get your prescription refilled in time. (If you spend your weekend drifting and unfocused you need your ADHD medication then, too. Just sayin’.)

The solution is simple: make a reminder in your phone to refill your prescription a week before your pills run out. Reminders will work better if you use a reminder app, like the Due App. Due doesn’t stop bugging you until you’ve done the task. (Sorry, Android users. The Due App is only for iPhones. If you have a good Android reminder app, let us know in the comments.)

Another trick a number of my ADHD coaching clients use is to keep a couple of extra pills stashed away just for these types of emergencies. Bingo. Problem solved. But, this is really just a band-aid. The best thing is to remember to refill your prescription.

These are all common ADHD medication mistakes I run into frequently with my new ADHD coaching clients. If you’re taking Adderall or Ritalin or another ADHD drug, why not do everything you can to help it work!

I’m curious. Which of these common ADHD medication mistakes are you making? And what steps will you take to avoid them? 

Let me know by adding a comment below.

Keep reading:

Dana Rayburn is an ADHD Coach in Oregon, but don’t worry… She works by telephone helping ADHD adults all over the world live more effortlessly and successfully with ADHD.

Sours: https://danarayburn.com/four-common-adhd-medication-mistakes-avoid/
Why Shouldn't You Take Medicine with Grapefruit Juice?


Lisdexamfetamine Dimesylate 30mg, Oral capsule

Foods that acidify the urine

· Severity: Moderate

·Notes for Consumers: Most foods are not expected to cause a problem with Lisdexamfetamine, so do not significantly alter your diet unless directed to do so by your health care professional. You may need to limit caffeine intake (food examples: coffee, teas, colas, and chocolate) while taking this medicine. Taking a high amount of Caffeine can increase the risk of irritability, nausea, nervousness, palpitations, problems with sleep (insomnia), rapid heartbeat, or other side effects.

·Notes for Professionals: Foods that acidify the urine, such as cranberry juice, orange juice, or those that contain ascorbic acid, vitamin C may increase amphetamine renal excretion. Patients should not significantly alter their diets, however as these changes are not expected to be clinically significant.

Lisdexamfetamine Dimesylate 30mg, Oral capsule

Acidic food

· Severity: Moderate

·Notes for Consumers: Most foods are not expected to cause a problem with this medication, so do not significantly alter your diet unless directed to do so by your health care professional. Acidic juices, like citrus juices (examples: orange juice, grapefruit juice) may decrease the absorption of this medication and are best avoided during the 1 hour before a dose, at the time of dosing, and for 1 hour after taking a dose. You may need to limit caffeine intake (food examples: coffee, teas, colas, and chocolate) while taking this medicine. Taking a high amount of caffeine can increase the risk of irritability, nausea, nervousness, palpitations, problems with sleep (insomnia), rapid heartbeat, or other side effects.

·Notes for Professionals: In general, food does not significantly interact with the amphetamine stimulants, a dose may be taken with or without food. However, certain gastrointestinal acidifying agents (e.g., certain fruit juices, etc.) can lower the oral absorption of amphetamines. To ensure proper absorption, it may be prudent for the patient to avoid citrus fruits and citrus juices 1 hour before a dose, at the time of dosing, and for the 1 hour following a dose. In addition, the excretion of amphetamines is increased in acidic urine and decreased in alkaline urine. Foods that acidify the urine, such as cranberry juice, orange juice, or those that contain vitamin C (ascorbic acid) may increase amphetamine renal excretion. Conversely, foods that alkalinize the urine, such as beets, dairy products, kale, spinach may slightly slow urinary excretion of amphetamines. Patients should not significantly alter their diets, however, as these changes in urinary pH from foods are not expected to be clinically significant for most patients.

Lisdexamfetamine Dimesylate 30mg, Oral capsule

Caffeine-containing Foods/Beverages

· Severity: Moderate

·Notes for Consumers: Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking this medicine. Also avoid medicines containing additional caffeine whenever possible. Side effects may get worse if you take excessive caffeine. Taking a high amount of caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, tremor, or other side effects.

·Notes for Professionals: CNS-stimulating actions of caffeine can be additive with other CNS stimulants. Patients may need to reduce, limit, or avoid caffeine intake. Excessive caffeine ingestion (via medicines, supplements or beverages including coffee, green tea, other teas, guarana, colas) may contribute to side effects like nervousness, irritability, insomnia, or tremor.

Lisdexamfetamine Dimesylate 30mg, Oral capsule

Foods that alkalinize urine

· Severity: Moderate

·Notes for Consumers: Most foods are not expected to cause a problem with Lisdexamfetamine, so do not significantly alter your diet unless directed to do so by your health care professional. You may need to limit caffeine intake (food examples: coffee, teas, colas, and chocolate) while taking this medicine. Taking a high amount of Caffeine can increase the risk of irritability, nausea, nervousness, palpitations, problems with sleep (insomnia), rapid heartbeat, or other side effects.

·Notes for Professionals: Foods that alkalinize the urine, such as beets, dairy products, kale, spinach may slightly slow urinary excretion of amphetamines. Patients should not significantly alter their diets, however as these changes are not expected to be clinically significant.

Lisdexamfetamine Dimesylate 30mg, Oral capsule


· Severity: Major

·Notes for Consumers: Combining marijuana with this medicine may increase blood pressure or heart rate. It can also increase nervousness or troubles with sleep. Contact your health care provider right away if you develop a fast or irregular heartbeat, a severe headache, or other new or unusual side effects.

·Notes for Professionals: Avoid administering marijuana and amphetamines together as concurrent use may result in adverse cardiovascular effects, such as tachycardia and cardiac arrhythmias. Marijuana is known to produce significant increases in heart rate and cardiac output lasting for 2-3 hours. Further, rare case reports of myocardial infarction and cardiac arrhythmias have been associated with marijuana use. Amphetamines have also been reported to produce a wide range of cardiovascular effects including cardiac arrhythmias, palpitations, and sinus tachycardia. Coadministration of marijuana with amphetamines may result in significant cardiovascular adverse events and thus, should be avoided.

Sours: https://www.wellrx.com/vyvanse/lifestyle-interactions/

Grapefruit vyvanse and

Just a spoonful …

Spoonful of pills, stockChances are, seven out of 10 adults like you take at least one prescription medication, and more than half of you take two prescribed medications. Also, 20 percent of adult Americans take at least five prescription medications per day.

Antibiotics are the most commonly prescribed drugs, followed by antidepressants and opioids. Nearly 75 million American adults take blood pressure medications. And cholesterol-lowering drugs, primarily statins, are also prescribed to more than 28 percent of American adults. For people younger than 19, vaccines, anti-asthma drugs, and antibiotics are the most commonly prescribed medications.

On a per capita basis, the top five states with the highest prescription usage are West Virginia, Kentucky, Mississippi, Arkansas, and Louisiana. Michigan ranks in the top 10 when it comes to pharmacy-filled prescriptions.

Drug actions and interactions are variable

As I detailed in a previous Health Yourself column, “Mood Swing,” drug effects on any one person may be different than expected. Persons taking more than one medication need to be aware of any interactions between them (i.e., drug-drug interactions). Specific foods, beverages, or dietary supplements also impact medications (nutrient/food-drug interactions), and certain medications interact with certain diseases a person may have (disease-drug interactions).

Children who take Adderall for ADHD, for example, should avoid taking it with apple juice or orange juice in the morning.A drug interaction of any kind represents a situation in which a substance, condition, or a person’s disorders can affect a drug’s performance. In some cases, a drug’s effects may increase or decrease; an interaction may even produce a new or different drug effect. Most food-drug interactions cause serious side effects, unbeknownst to the individual consuming either one.

Food-drug interactions represent an important and widely under-recognized reported source of medication “errors.”

Known food-drug interactions

The interaction of foods and drugs is a common hidden problem little understood by patients and—in some cases—their physicians. The interactions between natural products and drugs are based on the same pharmacokinetic and pharmacodynamic principles as drug-drug interactions. For example, several fruits and berries have recently been shown to contain agents that affect drug-metabolizing enzymes.

Grapefruit is the most well-known example, but also oranges, pomelo (citrus fruit similar to a grapefruit), and star fruit contain agents that inhibit the most important enzyme in drug metabolism.

Here are some specific examples of food-drug interactions of which we should all be aware, especially if we are taking these certain medicines or have these specific conditions.

High-potassium foods

Leafy greens, stockFoods high in potassium, like bananas, oranges, and leafy greens, interact with medications used to lower blood pressure (ACE inhibitors such as Capoten, Vasotec, and Lisinopril). Too much potassium can cause an irregular heartbeat and heart palpitations. High potassium levels can also interfere with kidney function, in those with chronic kidney disease.

Kale and other greens

Kale and other greens, including broccoli, cabbage, spinach, and brussels sprouts, are rich in vitamin K. High levels of vitamin K can reduce anti-blood-clotting effects of blood thinner medications like warfarin (Coumadin and Jantoven).

Grapefruit and other fruit juices

Grapefruit, stockOne of the most well-known food–drug interactions is grapefruit juice and reductase inhibitors, commonly known as statins, used to lower cholesterol and blood fat. Grapefruit juice, in large quantities (32 oz. or more per day), can inhibit enzymes that increase blood levels of statin drugs. Not all statins exhibit this interaction, however. The drugs most often affected include atorvastatin (Lipitor),simvastatin (Zocor),and lovastatin (Mevacor).Other statins, rosuvastatin (Crestor),pravastatin (Pravachol),and fluvastatin (Lescol),are less affected.

When grapefruit juice is consumed in combination with these drugs, there is an increased risk of statin-related side effects, most notably muscle toxicity, muscle pain and weakness, and worsening of asthma symptoms. There are other effects, too.

While the statins receive the most public attention for their interaction with grapefruit juice, other cholesterol-lowering drugs like calcium channel blockers used to lower blood pressure exhibit similar interactions with grapefruit juice. The calcium antagonist that is the most affected by fruit juice is felodipine (Plendil), demonstrating as high as a 200 percent increase in its effects.

Other drugs that directly interact with fruit juices, particularly grapefruit juice, include estrogen-containing oral contraceptives. Popular anti-anxiety disorder drugs like diazepam (Valium), temazepam (Restoril), and midazolam (Versed) also have a negative effect with the introduction of grapefruit juice.

Dairy products/calcium

In contrast to grapefruit juice, dairy products high in calcium may cause a chemical interaction; this is different from the metabolic interaction that occurs with fruit juices. Calcium ions bond with different drugs, decreasing absorption and overall effectiveness. Bread and other foods enriched with calcium exhibit similar interactions. Bisphosphonates, like Fosamax,that are used to prevent and treat osteoporosis are especially problematic when taken with dairy products.

Protein-Rich Foods

Meats, proteins, stockProtein-rich foods can interfere with, or potentiate the absorption of various medications, particularly Propranolol a beta-blocker drug used to treat high blood pressure, chest pain (angina), uneven heartbeats (atrial fibrillation), and performance anxiety.

Consuming a high-protein meal and concurrently taking propranolol can increase the beta-blocker’s bioavailability. When propranolol is taken with protein-rich foods, there is an increase in bioavailability up to 53 percent. Significant and notable side effects can include nausea, abdominal pain, constipation, and increases in liver and kidney problems.

Fiber-rich foods

Broccoli, etc., stock photoFiber works to bind drugs, resulting in their decreased concentration. For example, patients with diabetes who try to decrease their cholesterol levels by eating high-fiber foods after taking Metformin (the most widely used medication for diabetes) might be worsening their diabetic control since metformin blood levels are decreased when taken with large amounts of fiber (>30 g/d) in many individuals.

Foods containing Vitamin C

Vitamin C and foods and juices fortified with vitamin C and other vitamins can interact with different amphetamine-containing drugs like Adderall, commonly used to treat ADHD, narcolepsy, and athletic performance.

Vitamin C-containing foods consumed concurrently with Adderall may impair gastrointestinal absorption of food. Children who take Adderall for ADHD should avoid taking these drugs with apple or orange juice in the morning.

Tyramine-containing foods

Salami, stockTyramine is a chemical found in strong, aged cheeses, cured meats, and some beans and soy products. Tyramine exhibits significant interaction with monoamine oxidase inhibitors (MAOIs) used to treat depression, bacterial infections, and Parkinson’s disease. Interactions include spikes in blood pressure, severe headaches, fast heartbeat, chest pains, nausea, vomiting, and changes in vision.

Black licorice

Licorice derives from the root of Glycyrrhiza glabra. The licorice plant is a herbaceous perennial legume native to southern Europe and parts of Asia.

Interestingly, much of the black licorice sold in the United States doesn’t contain any actual licorice from the licorice plant. Instead, manufacturers add anise to the candy to give it a licorice-like flavor. Real black licorice candy interacts with digoxin (Lanoxin),which is used to treat heart failure and abnormal heart rhythms.

The licorice root can cause pseudoaldosteronism, a condition of fluid retention from increased sodium retention. The syndrome can cause increased blood pressure, irregular heartbeats, and potentially dangerous heart rhythms as well as muscle weakness and, in severe cases, paralysis.

What to do?

What you eat and drink can affect the way your medications work. Before taking any medication, it is important to know of any possible “food-drug interactions.” We need to keep track of the prescription and over-the-counter medicines we use, in addition to the vitamins, herbal supplements, and other dietary supplements we take. Unexpected side effects often come from unlikely sources.

  • Holbrook, A.M., et al. “Systematic overview of warfarin and its drug and food interactions.” Arch Intern Med. 2005; 165:1095-1106.
  • Leibovich, E.R., et al. “Food-drug interactions: Careful drug selection and patient counseling can reduce the risk in older patients.” Geriatrics. 2004; 59:19-33.
  • Libersa, C.C., et al. “Dramatic inhibition of amiodarone metabolism induced by grapefruit juice.” British Journal of Clinical Pharmacology. 2000; 49:373-378.
  • Liedholm, H., et al. “Mechanisms and variations in the food effect on propranolol bioavailability.” European Journal of Clinical Pharmacology. 1990;38:469-475.
  • Rabia, B., et al. “Food-drug interactions.” Oman Medical Journal. 2011; 26(2):77–83.
  • Summers, K.M. “Potential drug-food interactions with pomegranate juice.” Annals of Pharmacotherapy. 2006; 40:1472-1473.
  • Wallace, A.W., Amsden, G.W. “Is it really OK to take this with food? Old interactions with a new twist.” Journal of Clinical Pharmacology. 2202;42:437-443.
  • www.fda.gov/downloads/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/generaluseofmedicine/ucm229033.pdf
Sours: https://michigantoday.umich.edu/2017/05/15/dont-eat-this-if-you-take-that/
Don't Take This With That: Grapefruit, Drug Interaction

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